Caenorhabditis elegans histone methyltransferase MET-2 shields the male X chromosome from checkpoint machinery and mediates meiotic sex chromosome inactivation.
Meiosis is a specialized form of cellular division that results in the precise halving of the genome to produce gametes for sexual reproduction.Checkpoints function during meiosis to detect errors and subsequently to activate a signaling cascade that prevents the formation of Steering Wheel Products aneuploid gametes.Indeed, asynapsis of a homologo